The hypothalamic arcuate nucleus and the control of peripheral substrates.

Chemical ablation of the hypothalamic arcuate nucleus and its effect on electroencephalographic tracings and pain threshold in the tail flick test

  The present study was carried out to explore the possible involvement of the arcuate nucleus of the hypothalamus in the inhibitory descending pain control system associated with the tail flick test and EEG recordings. Adult male (NMRI) albino rats weighing 200 ± 20 g were used. Rats were divided into three groups: experimental, sham and control. The arcuate nucleus was destroyed unilaterally ...

P-5: Effect of Chronic Stress on Kiss-1 mRNA Expression in Male Rat Arcuate Hypothalamic Nucleus

Background Kisspeptin is a potent stimulator of the hypothalamic- pituitary-gonadal axis and may play a critical role in modulating of stress-induced suppression of reproduction. The aim of the present study was to investigate the effect of glucocorticoid receptor antagonist (RU486) and stress on expression of Kiss-1 mRNA in arcuate nucleus (ARC) of rat hypothalamus. MaterialsAndMethods Twenty ...

Expression of RFamide-Related Peptide-3 (RFRP-3) mRNA in Dorsomedial Hypothalamic Nucleus and KiSS-1 mRNA in Arcuate Nucleus of Rat during Pregnancy

Insulin Within the Arcuate Nucleus Has Paradoxical Effects on Nociception in Healthy and Diabetic Rats

Broad nervous circuits originate from the hypothalamic arcuate nucleus project to many parts of the brain which are related to pain perception. Insulin receptors have been found in the arcuate nucleus. Since nociception may be affected in type 1 diabetes, the present study aimed to investigate the intra-arcuate nucleus insulin role in pain perception in STZ-induced diabetic and healthy rats. Fo...

Lactation effect on the mRNAs expression of RFRP-3 and KiSS-1 in dorsomedial and arcuate nuclei of the rat hypothalamus

Introduction: Arginine-phenylalanine-amide-related peptide-3 (RFRP-3) and kisspeptin are believed to be inhibitor and stimulator of gonadotropin releasing hormone (GnRH) secretion, respectively. The aim of the present study was to compare the effect of lactation on the expression of RFRP-3 mRNA in dorsomedial hypothalamic nucleus (DMH) and KiSS-1 mRNA in arcuate nucleus (ARC) of hypothalamus...

The effect of Aluminium chloride injection in arcuate nucleus on sperm count and the weight of vas deferens and epididymis in rat

Aluminium is a blocker of voltage sensitive cakcium channels which intere the body from different soueces.this ion interferes with biological function of Ca++ion.because GnRH synthesis,secretion and spermatogenesis on vas deferens and epididymis sperm count and weight of these organs in male rats.the study was performed on four group of rats(n=49),in whom the arcuate nuleus was bilateraly cannu...